EURURO Vol. 71 No. 4

524 692

Table 1 (
Continued
)
Author, yr ofpublication
Populationinvestigated
Recruitment
criteria
No. ofpatients
Meanage (yr)
Mean PSA
(ng/ml)
MRI used; magnet
strength
Coil used
(no. channels)
Threshold for target
biopsy
Biopsy method;
approach
SB andTB cores
Definition of clinically
significant PCa
Thompson
et al., 2014
[20]
Negative or noprior biopsy
Elevated PSA and/orabnormal DRE
150 62.0
5.6 Unknown; 1.5 and
3.0 Tesla
PPA (32)
PIRADS 3 or higher Cognitive TRUS and
MRI/TRUS fusion;transperineal
Yes Multiple definitions; applied
definition:-Gleason score 3 + 4 and>
5% grade 4 component and
<
50% cores positive
-or Gleason score 3 + 3 and<
5% grade 4 component and
<
30% cores positive
-or MCCL 8 mm
Pokorny
et al., 2014
[23]
No prior biopsy Elevated PSA and/or
abnormal DRE
142 63.0
5.3 Magnetom Skyra
(Siemens); 3 Tesla
PPA
PIRADS 3 or higher In-bore MRI; transrectal
Yes -Gleason score = 3 + 3 and
MCCL 6 mm-or Gleason score = 3 + 4 andMCCL 4 mm-or Gleason score 4 + 3
Jambor et al.,
[10_TD$DIFF] 2015
No prior biopsy Elevated PSA
53 66.0
7.4 Magnetom Verio
(Siemens); 3 Tesla
PPA
PIRADS 4 or higher Cognitive TRUS;
transrectal
Yes -Gleason score 3 + 4
-or Gleason score = 3 + 3 andMCCL 3 mm
Boesen et al.,
[10_TD$DIFF] 2015
[75]
Negative priorbiopsy
Elevated PSA and/orabnormal DRE
83 63.0
11.0 Achieva (Philips);
3 Tesla
PPA (6)
No thresholddefined
Cognitive TRUS;transrectal
Yes Epstein criteria
Habchi et al., 2014
[14_TD$DIFF] [76]
Mixedpopulation
Elevated PSA and/orabnormal DRE
204 61.8
8.3 Discovery (GE); 3 Tesla PPA
PIRADS 2 or higher Cognitive TRUS;
transrectal
Yes Gleason score 3 + 4
Sonn et al., 2014
[11_TD$DIFF] [77]
Negative priorbiopsy
Elevated PSA
105 65.0
7.5 Trio Tim (Siemens);
3 Tesla
PPA
PIRADS 2 or higher MRI/TRUS fusion;
transrectal
Yes -Gleason score 3 + 4
-or Gleason score = 3 + 3 andMCCL 4 mm
Quentin et al., 2014
[13_TD$DIFF] [47]
o prior biopsy Elevated PSA
128 66.1
6.7 Magnetom Trio
(Siemens); 3 Tesla
PPA (6)
No thresholddefined
In-bore MRI; transrectal
Yes -Gleason score 3 + 4
-or Gleason score = 3 + 3 andTCCL
>
5 mm
Pepe et al., 2015
[15_TD$DIFF] [78]
Negative priorbiopsy
Elevated PSA
100 64.0
8.6 Achieva (Philips);
3 Tesla
PPA (16)
PIRADS 4 or higher Cognitive TRUS;
transperineal
Yes -Gleason score 3 + 4
-or Gleason score = 3 + 3 andTCCL
>
50%
DRE = digital rectal examination; ERC = Endorectal coil; MMCL = maximum cancer core length; MRI = magnetic resonance imaging; PCa = prostate cancer; PIRADS = prostate imaging reporting and data system; PPA = PelvicPhased Array; PSA = prostate-specific antigen; SB = systematic biopsy; TB = target biopsy; TCCL = total cancer core length; TRUS = transrectal ultrasound.
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