523 692
Junker et al., 2013
[7_TD$DIFF]
[60]
Negative prior
biopsy
Elevated PSA
73 62.0
6.4 Magnetom Skyra
(Siemens); 3 Tesla
PPA (18)
PIRADS sum score
7
MRI/TRUS fusion;
transrectal
Yes Gleason score 4 + 3
Rosenkrantz et al.,
2013
[7_TD$DIFF]
[61]
Negative or no
prior biopsy
Elevated PSA
42 63.0
7.4 Unknown; 3 Tesla
PPA
In tumour
suspicious/abnormal
MRI; no threshold
defined
Cognitive TRUS;
transrectal
Yes d’Amico classification
(intermediate and high risk)
Delongchamps et al.,
2013
[8_TD$DIFF]
[62]
No prior biopsy Elevated PSA and/or
abnormal DRE
391 63.9
8.5 Unknown; 1.5 Tesla
Combined ERC
and PPA
Sum score of 4 and
6
Cognitive TRUS and
MRI/TRUS fusion;
transrectal
Yes Microfocal disease = Gleason
score = 3 + 3 and MCCL
<
5 mm and single core
positive
Fiard et al., 2013
[7_TD$DIFF]
[63]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE
30 64.0
6.3 Achieva (Philips);
3 Tesla
PPA (32)
PIRADS sum score
5
MRI/TRUS fusion;
transrectal
Yes -d’Amico classification
(intermediate and high risk)
-or Gleason score 3 + 4
-or TCCL 10 mm
Kuru et al., 2013
[31]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE
347 65.3
9.9 Magnetom Trio
(Siemens); 3 Tesla
PPA
Irrespective of MRI
findings
MRI/TRUS fusion;
transperineal
Yes NCCN criteria (intermediate
and high risk)
[9_TD$DIFF]
Kaufmann et al.,
[10_TD$DIFF]
2015
[64]
Negative prior
biopsy
Elevated PSA and
abnormal MRI
35 68.0
9.4 Magnetom Espree
(Siemens); 1.5 Tesla
ERC
Irrespective of MRI
findings
In-bore MRI; transrectal
Yes d’Amico classification
(intermediate and high risk)
and Epstein criteria
Penzkofer et al.,
[10_TD$DIFF]
2015
[65]
Mixed
population
Abnormal MRI
52 65.0
15.3 Signa (GE); 3 Tesla
Combined ERC
and PPA
No threshold
defined
In-bore MRI;
transperineal
No Gleason score 3 + 4
Schimmoller et al.,
2014
[11_TD$DIFF]
[66]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE and
abnormal MRI
235 65.7
9.9 Magnetom Trio
(Siemens); 3 Tesla
PPA (6)
No threshold
defined
In-bore MRI; transrectal
No Gleason score 4 + 3
Shakir et al., 2014
[11_TD$DIFF]
[45]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE and
abnormal MRI
1003 62.1
6.7 Achieva (Philips);
3 Tesla
Combined ERC
and PPA (16)
In tumour
suspicious/abnormal
MRI; no threshold
defined
MRI/TRUS fusion;
transrectal
Yes Gleason score 4 + 3
Rastinehad et al.,
2014
[11_TD$DIFF]
[30]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE and
abnormal MRI
105 65.8
9.2 Magnetom Verio
(Siemens); 3 Tesla
Combined ERC
and PPA (16)
Low risk using NIH
criteria
MRI/TRUS fusion;
transrectal
Yes SB: Epstein criteria (SB) TB:
-Gleason score 3 + 4
-or MRI lesion
>
0.2 cc
Mozer et al.,
[10_TD$DIFF]
2015
[67]
No prior biopsy Elevated PSA and
abnormal MRI
152 63.0
6.0 Achieva (Philips);
1.5 Tesla
PPA
PIRADS 2 or higher MRI/TRUS fusion;
transrectal
Yes -Gleason score 3 + 4
-or Gleason score = 3 + 3 and
MCCL 4 mm
Salami et al., 2014
[11_TD$DIFF]
[68]Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE and
abnormal MRI
175 64.9
7.1 Magnetom Verio
(Siemens); 3 Tesla
Combined ERC
and PPA (16)
PIRADS 2 or higher MRI/TRUS fusion;
transrectal
Yes SB: Epstein criteria TB:
-Gleason score 3+ 4
-or MRI lesion
>
0.2 cc
Salami et al.,
[10_TD$DIFF]
2015
[69]Negative prior
biopsy
Elevated PSA and/or
abnormal DRE and
abnormal MRI
140 65.8
9.0 Magnetom Verio
(Siemens); 3 Tesla
Combined ERC
and PPA (16)
PIRADS 2 or higher MRI/TRUS fusion;
transrectal
Yes SB: Epstein criteria TB:
-Gleason score 3+ 4
-or MRI lesion
>
0.2 cc
[12_TD$DIFF]
Shoji et al.,
[10_TD$DIFF]
2015
[70]No prior biopsy Elevated PSA and/or
abnormal DRE and
abnormal MRI
20 70.0
7.4 Signa (GE); 1.5 Tesla PPA (8)
PIRADS 2 or higher MRI/TRUS fusion;
transperineal
Yes -Gleason score 3 + 4
-MCCL
>
4 mm
Roethke et al., 2014
[11_TD$DIFF]
[27] Negative or no
prior biopsy
Elevated PSA and
abnormal MRI
64 64.5
8.3 Magnetom Trio
(Siemens); 3 Tesla
PPA
No threshold
defined
MRI/TRUS fusion;
transperineal
No Gleason score 3 + 4
Ploussard et al.,
2014
[11_TD$DIFF]
[71]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE and
abnormal MRI
91 63.0
6.0 Intera (Philips);
1.5 Tesla
PPA
PIRADS 3 or higher cognitive TRUS;
transrectal
Yes Epstein criteria
Kuru et al., 2014
[72]
Negative prior
biopsy
Elevated PSA and
abnormal MRI
74 64.0
11.3 Unknown; 3 Tesla
PPA
In tumour
suspicious/abnormal
MRI; no threshold
defined
MRI/TRUS fusion;
transperineal
Yes Gleason score 4 + 3
Radtke et al.,
[10_TD$DIFF]
2015
[48]
Negative or no
prior biopsy
Elevated PSA and/or
abnormal DRE
294 64.0
7.3 Unknown (Siemens);
3 Tesla
PPA
PIRADS 2 or higher MRI/TRUS fusion;
transperineal
Yes Gleason score 3 + 4
Iwamoto et al.,
2014
[13_TD$DIFF]
[73]
No prior biopsy Elevated PSA
238 69.2
9.6 Achieva (Philips) and
Magnetom Skyra
(Siemens); 1.5 and
3 Tesla
In tumour
suspicious/abnormal
MRI; no threshold
defined
Cognitive TRUS;
transrectal
Yes Gleason score 3 + 4
E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 5 1 7 – 5 3 1
523