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EAU Recommendation

The Role of Urodynamics in the Evaluation of Urinary

Incontinence: The European Association of Urology

Recommendations in 2016

Arjun K. Nambiar

a , * ,

Gary E. Lemack

b ,

Christopher R. Chapple

c ,

Fiona C. Burkhard

d ,

on behalf of the European Association of Urology

a

Department of Urology, Freeman Hospital, Newcastle-upon-Tyne, UK;

b

Department of Urology, University of Texas Southwestern Medical Centre, TX, USA;

c

Royal Hallamshire Hospital, Sheffield, UK;

d

Department of Urology, University Hospital Bern, Bern, Switzerland

Urodynamic studies are defined simply as

[2_TD$DIFF]

a functional

study of the lower urinary tract, usually comprising free

uroflowmetry, postvoid residual (PVR) measurement, filling

and voiding cystometry

[1,2] .

The role and utility of

urodynamics as a diagnostic and prognostic tool for

patients with urinary incontinence, and lower urinary

tract symptoms in general, is a topic of on-going debate in

functional urology forums across the globe. The purpose of

this article is to clarify and reiterate the position of the

European Association of Urology (EAU) guideline office on

the matter as it currently stands. We also review some of

the evidence on which these recommendations are based,

as well as some of the controversies in the interpretation of

this evidence.

The overall recommendations from the guidelines

regarding the use of urodynamics in the evaluation of

incontinence can be simply summarised as follows:

A good history and clinical evaluation should be all

that are required to help decide the best treatment for

uncomplicated urinary incontinence.

Urodynamics may help if there is uncertainty about

the best form of invasive treatment to pursue.

Always perform urodynamics to the highest possible

quality standards for the results to be valid and useful.

To arrive at these conclusions, the guideline panel

conducted a thorough and systematic evaluation of the

available evidence. The EAU guidelines are unique in that

the searches are updated annually and therefore there is an

annual appraisal of the evidence to identify any new

important research that may influence or change the

recommendations.

[3_TD$DIFF]

Consequently,

[4_TD$DIFF]

it provides readers with

the most up-to-date evaluation of the evidence relating to

urology.

These are not the only international guidelines pertain-

ing to urodynamics, however. For comparison, we examine

the statements and recommendations, in full, of various

guideline groups regarding the role of urodynamics in the

management of urinary incontinence (UI), as shown in

Table 1

.

Two things are apparent from these recommendations.

First, the assigned evidence grades (where stated) appear to

be low to moderate. Second, it is important not to confuse

recommendations for stress UI (SUI) with urgency UI or UI

in general.

Grades of recommendation tend to be based on the level

of evidence available when reviewing a topic. Urodynamic

studies have not been extensively evaluated in randomised

control trials, for reasons we can only speculate about.

However, a relatively recent trial has been conducted by the

Urinary Incontinence Treatment Network in the USA. Aptly

named the VALUE study

[6]

, its aim was to assess the value

of urodynamic evaluation in a multicentre, randomised,

noninferiority design comparing the results of office

evaluation alone to office evaluation plus urodynamics

among women for whom surgery was planned for stress-

predominant UI. The primary outcome was a reduction of

more than 70% in the Urogenital Distress Inventory score,

and a response of ‘‘much better’’ or ‘‘very much better’’ for

E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 5 0 1 – 5 0 3

ava ilable at

www.sciencedirect.com

journal homepage:

www.eu ropeanurology.com

* Corresponding author. Department of Urology, Freeman Hospital, Freeman Road, Newcastle-upon-Tyne, NE7 7DN, UK. Tel.

+44 790 7824797

.

E-mail address:

arjunknambiar@gmail.com

(A.K. Nambiar).

http://dx.doi.org/10.1016/j.eururo.2016.09.045

0302-2838/

#

2016 European Association of Urology. Published by Elsevier B.V. All rights reserved.