EURURO Vol. 71 No. 4

e u r o p e a n u r o l o g y , vo l . 7 1 , n o . 4 , A p r i l 2 0 1 7

570

Comparative Effectiveness of Newer Medications for Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis

P. Dahm, M. Brasure, R. MacDonald, C.M. Olson, V.A. Nelson, H.A. Fink, B. Rwabasonga, M.C. Risk,

T.J. Wilt

Drugs and drug combinations newly used to treat lower urinary tract symptoms

attributed to benign prostatic hyperplasia did not show outcomes superior to

traditional alpha-blocker treatment. Given the lack of superior outcomes and less

assurance of their safety, their current value appears low.

582

Medical Treatment of Male Lower Urinary Tract Symptoms: Does One Fit All?

M. Rieken, C. Gratzke

584

Ex Vivo Model of Human Penile Transplantation and Rejection: Implications for Erectile Tissue Physiology

N.A. Sopko, H. Matsui, D.M. Lough, D. Miller, K. Harris, M. Kates, X. Liu, K. Billups, R. Redett,

A.L. Burnett, G. Brandacher, T.J. Bivalacqua

Penile transplant models are lacking, and it is unknown how rejection and

immunosuppression affect erectile physiology. Ex vivo mixed lymphocyte reaction

simulates transplantation and demonstrated that rejection and certain

immunosuppression treatments, such as cyclosporine A, impair erectile function.

594

Getting Ready for Penile Transplantation

M. Albersen

596

Sentinel Node Procedure in Prostate Cancer: A Systematic Review to Assess Diagnostic Accuracy

E.M.K. Wit, C. Acar, N. Grivas, C. Yuan, S. Horenblas, F. Liedberg, R.A. Valdes Olmos,

F.W.B. van Leeuwen, N.S. van den Berg, A. Winter, F. Wawroschek, S. Hruby, G. Janetschek,

S. Vidal-Sicart, S. MacLennan, T.B. Lam, H.G. van der Poel

The accuracy of sentinel node biopsy (SNB) in detecting positive lymph nodes in

prostate cancer appears to have diagnostic accuracy comparable to that of

extended pelvic lymph node dissection (ePLND). However, SNB may not have any

additional diagnostic value over and above ePLND.

606

Partial Nephrectomy Versus Radical Nephrectomy for Clinical T1b and T2 Renal Tumors: A Systematic Review and Meta-analysis of Comparative Studies

M.C. Mir, I. Derweesh, F. Porpiglia, H. Zargar, A. Mottrie, R. Autorino

Partial nephrectomy (PN) is a viable treatment option for larger renal tumors, as it

offers acceptable surgical morbidity, equivalent cancer control, and better

preservation of renal function, with potential for better long-term survival. In the

subset of T2 tumors its use should be more selective, and specific patient and tumor

factors should be considered. Further investigation, ideally in a prospective

randomized fashion, is warranted to better define the role of PN in this challenging

clinical scenario.

618

EAU-ESTRO-SIOG Guidelines on Prostate Cancer. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent

N. Mottet, J. Bellmunt, M. Bolla, E. Briers, M.G. Cumberbatch, M. De Santis, N. Fossati, T. Gross,

A.M. Henry, S. Joniau, T.B. Lam, M.D. Mason, V.B. Matveev, P.C. Moldovan, R.C.N. van den Bergh,

T. Van den Broeck, H.G. van der Poel, T.H. van der Kwast, O. Rouvière, I.G. Schoots, T. Wiegel,

P. Cornford

The 2016 European Association of Urology prostate cancer guidelines summarise

the most recent findings and provide recommendations for clinical practice. The

knowledge in the field of diagnosis, staging, and treatment of localised prostate

cancer is rapidly evolving.

Reviews

Prostate Cancer

Reconstructive

Urology

Kidney Cancer

Guidelines

Benign Prostatic

Hyperplasia