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the Patient Global Impression of Improvement at 12 mo.

Some 630 women were enrolled in the study, with

538 included in the final intention-to-treat analysis. The

result was 76.9% treatment success in the urodynamic

testing group versus 77.2% in the office evaluation–only

group, consistent with noninferiority. Interestingly, the

study did show that women undergoing urodynamics were

less likely to receive a diagnosis of overactive bladder (25%

vs 41%) and more likely to be diagnosed with voiding phase

dysfunction (11.9% vs 2.2%), but this did not to lead to any

significant differences in treatment selection or outcomes.

The principal finding of this, and some of the secondary

analyses, was that while the diagnosis may have changed

after urodynamics, it was uncommon for the surgical

procedure to be altered. In addition, regardless of any

change in diagnosis or surgical plan, the outcome was not

affected by performing urodynamics in this select group of

patients. Importantly, this study was based on a very select

group of women with SUI unlikely to suffer postoperative

complications.

A similar European study

[7]

randomised 109 women for

whom urodynamics results were discordant with clinical

assessment to either immediate surgery or individually

tailored therapy based on urodynamics. They concluded

that immediate surgery, irrespective of the result of

urodynamic studies, did not result in inferior outcomes.

This brings us to the conundrum of the true utility of

urodynamics in investigating

[1_TD$DIFF]

patients

[5_TD$DIFF]

’ UI. Most practi-

tioners accept the evidence that there is poor same-session

repeatability

[8]

and even interoperator repeatability for

urodynamics. Furthermore, if we accept the available

evidence that urodynamic studies do not influence the

outcomes of conservative or drug management for any type

of UI or outcomes after surgery for uncomplicated SUI

[5,9]

,

then it becomes essential to ask whether there is a role for

urodynamics as a preliminary investigation in patients

with UI.

The answer, as is so often the case in functional urology,

is not a straightforward one. The EAU guideline panel has

taken a pragmatic approach and states that urodynamics,

when used, should always be performed to a standard

adhering to ICS guidelines with good quality control, always

aim to replicate the patient’s symptoms and always

be interpreted based on the individual clinical context.

We further state that it should not be used routinely

before offering treatment for uncomplicated UI, but may be

performed if the findings may change the choice of invasive

treatment. This leaves the decision very much in the hands

of the consulting clinician, and this is quite deliberate. The

aim of the guideline is to provide the clinician with an

appraisal of the available evidence that is aimed to help

themmake the most appropriate decision for the individual

patient.

As discussed in the section devoted to treatment of the

patient with complicated incontinence, there are certain

clinical scenarios where urodynamics can clearly provide

unique and valuable information that cannot be easily

obtained elsewhere. Patients who have had prior surgical

treatments and have persistent or worsening incontinence,

or patients with mixed incontinence who have not

responded to conservative and medical management are

two good examples for which urodynamic evaluation may

help in guiding management. Other examples are noted in

Figure 1 .

In summary, there is currently quality evidence demon-

strating that in a patient with straightforward stress

incontinence (no significant postvoid residual, no prior

lower urinary tract surgeries, either pure SUI or stress-

Table 1 – Recommendations by international guideline groups on the role of urodynamics in the management of urinary incontinence

European Association of Urology urinary incontinence guideline recommendations

[5]

Clinicians carrying out urodynamics in patients with urinary incontinence should:

- Ensure that the test replicates the patient’s symptoms

- Interpret results in the context of the clinical problem

- Check recordings for quality control

- Remember there may be physiological variability within the same individual (grade C)

Advise patients that the results of urodynamics may be useful in discussing treatment options, although there is limited evidence that performing urodynamics

will predict the outcome of treatment for uncomplicated urinary incontinence (grade C)

Do not routinely carry out urodynamics when offering treatment for uncomplicated urinary incontinence (grade B)

Perform urodynamics if the findings may change the choice of invasive treatment (grade B)

National Institute for Health and Care Excellence (2015)

[4]

Do not perform multichannel cystometry, ambulatory urodynamics or videourodynamics before starting conservative management (2006, amended 2013)

After undertaking a detailed clinical history and examination, perform multichannel filling and voiding cystometry before surgery in women who have:

- Symptoms of OAB leading to a clinical suspicion of detrusor overactivity, or

- Symptoms suggestive of voiding dysfunction or anterior compartment prolapse, or

- Had previous surgery for stress incontinence (2006, amended 2013)

Do not perform multichannel filling and voiding cystometry in the small group of women where pure SUI is diagnosed based on a detailed clinical history and

examination (2006, amended 2013)

Consider ambulatory urodynamics or videourodynamics if the diagnosis is unclear after conventional urodynamics (2006, amended 2013)

Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction/American Urological Association (2012)

[3]

‘‘Clinicians may perform multi-channel urodynamics in patients with both symptoms and physical findings of stress incontinence who are considering invasive,

potentially morbid or irreversible treatments’’ (option; evidence strength: grade C)

‘‘Clinicians should perform repeat stress testing with the urethral catheter removed in patients suspected of having SUI who do not demonstrate this finding with

the catheter in place during urodynamic testing’’ (recommendation; evidence strength: grade C)

OAB = overactive bladder; SUI = stress urinary incontinence

E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 5 0 1 – 5 0 3

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