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[(Fig._1)TD$FIG]

Fig. 1 – Change in Functional Assessment of Cancer Therapy–Prostate (FACT-P) domain scores over time. The grey bars represent the minimal clinically

important difference range.

D

MMRM

is the adjusted mean (standard error) change from baseline with enzalutamide versus bicalutamide at wk 61

(mixed model repeated measures [MMRM] analysis).

D

PMM

is the adjusted mean (standard error) change from baseline with enzalutamide versus

bicalutamide at wk 61 (pattern mixture model [PMM] analysis).

EQ-5D = European Quality of Life 5-Domain Scale; FACT-G = Functional Assessment of Cancer Therapy–General; FAPSI-8 = FACT Advanced Prostate

Symptom Index-8; PCS = prostate cancer subscale.

E U R O P E A N U R O L O G Y 7 1 ( 2 0 1 7 ) 5 3 4 – 5 4 2

538